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Berberine and Finesteride - miles14r - 01-05-2017
Does anyone know if it is safe to combine berberine with finesteride? I've heard that berberine inhibits the liver enzyme that metabolizes finesteride so it's something of a concern.
RE: Berberine and Finesteride - Scott Stevenson - 01-05-2017
(01-05-2017, 12:38 AM)miles14r Wrote: Does anyone know if it is safe to combine berberine with finesteride? I've heard that berberine inhibits the liver enzyme that metabolizes finesteride so it's something of a concern.
CYP3A4 seems to be the enzyme in question and there is concern for interaction and both finateride and berberine are metabolized by this enzyme:
https://www.ncbi.nlm.nih.gov/pubmed/8654202
https://www.ncbi.nlm.nih.gov/pubmed/21569619
-S