Integrative Bodybuilding › Visitor's Forums › Articles, Videos and Samples v
Berberine and Finesteride

Thread Rating:
  • 0 Vote(s) - 0 Average
  • 1
  • 2
  • 3
  • 4
  • 5
Thread Modes
Berberine and Finesteride
miles14r Offline
Junior Member
**
Posts: 1
Threads: 1
Thanks Received: 1 in 1 posts
Thanks Given: 0
Joined: Nov 2016
Reputation: 0
#1
01-05-2017, 12:38 AM
Does anyone know if it is safe to combine berberine with finesteride? I've heard that berberine inhibits the liver enzyme that metabolizes finesteride so it's something of a concern.
[-] The following 1 user says Thank You to miles14r for this post:
  • Scott Stevenson
Reply
Scott Stevenson Offline
Super Moderator
******
Super Moderators
Posts: 7,297
Threads: 119
Thanks Received: 2,393 in 1,868 posts
Thanks Given: 1,882
Joined: Apr 2012
Reputation: 12
#2
01-05-2017, 11:02 AM
(01-05-2017, 12:38 AM)miles14r Wrote: Does anyone know if it is safe to combine berberine with finesteride? I've heard that berberine inhibits the liver enzyme that metabolizes finesteride so it's something of a concern.

CYP3A4 seems to be the enzyme in question and there is concern for interaction and both finateride and berberine are metabolized by this enzyme:

https://www.ncbi.nlm.nih.gov/pubmed/8654202

https://www.ncbi.nlm.nih.gov/pubmed/21569619

-S
-Scott

Thanks for joining my Forum! dog

The above and all material posted by Scott Stevenson are Copyright © Scott W. Stevenson and Evlogia QiWorks, LLC. All Rights Reserved.
Reply


Forum Jump:


Users browsing this thread: 1 Guest(s)